Lyvioni is a medircine that contains the active substance lenvatinib. it is used to treat progressive or advanced thyroid cancer in adults whenradioactive iodine treatment has not helped to stop the disease.

1. What Lyvioni is and what it is used for

What Lyvioni is

Lyvioni is a medicine that contains the active substance lenvatinib. it is used to treat progressive or advanced thyroid cancer in adults when radioactive iodine treatment has not helped to stop the disease.

How Lyvioni works

Lyvioni blocks the action of proteins called receptor tyrosine kinases (RTKs),which are involved in the development of new blood vessels that supply oxygen and nutrients to cells and help them to grow.These proteins can be present in high amounts in cancer cells,and by blocking their action Lyvioni may slow the rate at which the cancer cells multiply and the tumour grows and help to cut off the blood supply that the cancer needs.

2. How to take Lyvioni

Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.

How much to take

*The recommended dose of Lyvioni is usually 24 mg once a day

(2 capsules of 10 mg and 1 capsule of 4 mg).

* lf you have severe liver or kidney problems the recommended dose is 14 mg once a day

(1 capsule of 10 mg and 1 capsule of 4 mg).

Your doctor may reduce your dose if you have problems with side effects.

Taking this medicine

*You can take the capsules with or without food.

*Swallow the capsules whole with water.

*Take the capsules at about the same time each day.

*Caregivers should not open the capsules to avoid exposure to the contents of the capsule.

3.Possible side effects

Very common (may affect more than 1 in 10 people)

*high or low blood pressure

*loss of appetite or weight loss

*feeling sick and being sick, constipation, diarrhoea, abdominal pain, indigestion

*feeling very tired or weak

*hoarse voice

*swelling of the legs

*rash

*dry,sore, or inflamed mouth, odd taste sensation

*joint or muscle pain

*hair loss